Come As You Are - Assessing the Efficacy of a Nurse Case Management HIV Prevention and Care Intervention Among Homeless Youth

Come As You Are (CAYA) Pre-Exposure Prophylaxis (PrEP) adherence study
Overview: This study aims to enrich the scientific understanding of PrEP adherence and barriers and access to HIV prevention health services among sexual and gender minority (SGM) youth experiencing homelessness (YEH). Recruitment of this hard-to-reach, understudied population of high-risk youth provides an exceptional opportunity to examine engagement of SGM homeless youth in PrEP adherence measurement, qualitatively assess barriers and facilitators to access to and engagement in HIV prevention and care, and assess the role of stress on risk behaviors among SGM YEH.
Assessment of COVID-19 antibodies and transmission reduction strategies among Youth Experiencing Homelessness
Overview: Participants for this supplement (YEH 16-25 years old) are recruited from sites already participating in the parent CAYA study. To meet the additional aims of this supplement, measures related to knowledge of and adherence to COVID-19 transmission reduction strategies (i.e. hand washing, masking, social distancing, stay-at home orders) were added to existing measures for mental health symptoms (i.e. stress, distress, anxiety), behavioral risks (i.e. condomless sex, trade sex, drug use), and determinants of health (i.e. housing). Additionally, COVID-19 antibody is conducted testing.